IS ORTHOVISC® RIGHT FOR YOU

IS ORTHOVISC® RIGHT FOR YOU?

This is a question you may be asking yourself. Take a moment to review the following patient profiles. Do you see yourself in any of them? If so, it may be time to talk to your doctor and determine if ORTHOVISC® is right for you.

Name: John	Age: 65
Candidate for ORTHOVISC®
Diagnosed 6 years ago. MRIMagnetic Resonance Imaging (MRI) A special imaging technique used to image internal structures of the body particularly the soft tissues findings show OA in the left knee
History of heart disease with two years post- coronary stent
Moderate Pain- Current activity level affected by stiffness, diminished range of motion, interferes with daily function and ability to maintain exercise regimen
Previous Treatment OTC NSAIDsNSAIDs A nonsteroidal anti-inflammatory drug such as ibuprofen— insufficient pain relief IA corticosteroid injectionsCorticosteroid Injections A steroid hormone produced by the adrenal cortex (the outer portion of the adrenal glands); administered as drugs they reduce swelling and decrease the body's immune response- 4 in 3 years Completed Physical Therapy Total Joint ReplacementTotal Joint Replacement Repair of a damaged joint by replacing with a synthetic joint implant, made of either plastic, ceramic, titanium or stainless steel, in an effort to return normal function to affected joint discussed but not ready at this time

Name: Jane	Age: 58
Candidate for ORTHOVISC®
Diagnosed 4 years ago with OA in the left knee
History of GastrointestinalGastrointestinal Relating to or affecting both stomach and intestine Issues
Mild to Moderate Pain that interferes with daily function, stiffness, pain at night, range of motion- standing/bending
Previous Treatment OTC NSAIDs— adverse events IA corticosteroid injections- 2 in 12 months Completed Physical Therapy Discussed Arthroscopic Intervention but did not want to proceed at this time

Name: Tom	Age: 42
Candidate for ORTHOVISC®
Diagnosed with degenerative condition of the knee 3 months ago
History of previous athletic injuries, family history of diabetes and arthritis. Knee scopeKnee Scope Examination of a knee through an endoscope (an instrument for visualizing the interior of a hollow organ) 3 months ago and continues to have pain post scope.
Moderate Pain causing pain at rest, wake during sleeping, pain and stiffness in joints, noise in joint during movement
Previous Treatment Heat, ice, massage and topical medications AcetaminophenAcetaminophen A drug used to relieve pain and fever COX-2 InhibitorsCOX-2 Inhibitors Any of a class of nonsteroidal anti-inflammatory drugs to relieve the pain and inflammation of arthritis and thought to minimize gastrointestinal side effects— safety concern IA corticosteriod injections 4 in 2 years Physical therapy Knee scope

Name: Kathy	Age: 50
Candidate for ORTHOVISC®
Diagnosed 5 years ago with OA of the knee
History of obesity with dramatic weight loss occurring 7 years ago
Moderate Pain causing crackling sensations and joint buckling which interfered with activities of daily living
Previous Treatment Heat, ice, acupuncture and dietary supplements AcetaminophenAcetaminophen A drug used to relieve pain and fever OTC NSAIDs— inadequate pain relief COX-2 Inhibitors— effectiveness beginning to diminish Physical therapy IA corticosteroid injections 2 in 1 year