Glossary of Key Terms
Browse the definitions below to find explanations of many of the more technical terms you may come across on this site and in other resources on knee pain and treatment.
- Acetaminophen
A drug used to relieve pain and fever
Back to top- Acupuncture
Originally a Chinese practice of inserting fine needles through the skin at specific points especially to cure disease or relieve pain
Back to top- Analgesics
Agents for producing pain relief
Back to top- Arthralgia
Pain in one or more joints
Back to top- Arthritis
Inflammation of a joint or joints resulting in pain, swelling and stiffness
Back to top- Arthroplasty
The operative formation or restoration of a joint
Back to top- Arthroscope
An instrument for visualizing the interior of a hollow organ that is inserted through an incision near a joint (as the knee) and is used for the visual examination, diagnosis, and treatment of the interior of a joint
Back to top- Arthroscopy
Examination of a joint with a scope
Back to top- Articular
Of or relating to a joint
Back to top- Articular Cartilage
Cartilage that covers the articular surfaces of bones
Back to top- Aseptic
Freedom from infection, sterile
Back to top- Aspiration
The withdrawal of fluid from the body
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Derived from birds
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A substance or mixture of substances that in a solution tends to stabilize and neutralize, within limits, both acids and bases
Back to top- Cartilage
A usually translucent somewhat elastic tissue that composes most of the skeleton
Back to top- Chronic Synovial Inflammation
Inflammation of synovial fluid lasting for a long period of time or marked by frequent recurrence
Back to top- CMS
Center for Medicare and Medicaid Services
Back to top- Co morbidities
Occurring or existing concurrently but unrelated pathological or disease process
Back to top- Contra lateral
Occurring on, affecting, or acting in conjunction with a part on the opposite side of the body
Back to top- Contraindicated
To make a treatment or procedure inadvisable
Back to top- Corticosteroid Injections
A steroid hormone produced by the adrenal cortex (the outer portion of the adrenal glands); administered as drugs they reduce swelling and decrease the body's immune response
Back to top- COX-2 Inhibitors
Any of a class of nonsteroidal anti-inflammatory drugs to relieve the pain and inflammation of arthritis and thought to minimize gastrointestinal side effects
Back to top- Degenerative Arthritis/Degenerative Joint Disease
Disease that leads to the gradual deterioration of a joint; also called Osteoarthritis.
Back to top- Efficacy
Capacity for producing a desired result or effect
Back to top- Elastoviscous/Elastoviscosity
And ideal viscosupplementation solution enhances elastic (high impact- such as running) and viscous (low impact- such as walking) properties in a knee with osteoarthritis
Back to top- Endorphins
Any of a group of endogenous peptides that bind chiefly to opiate receptors (in the cell membrane) and produce some of the same pharmacological effects (pain relief) as those of opiates (dulls the senses and induces relaxation)
Back to top- Gastrointestinal
Relating to or affecting both stomach and intestine
Back to top- Glucocorticoids (steroids)
Any of a group of steroid hormones, such as cortisone, that are produced by the adrenal cortex (the outer portion of the adrenal glands) and have anti-inflammatory properties
Back to top- Homeostasis
The maintenance of relatively stable internal physiological conditions such as body temperature or the pH of blood
Back to top- Hyaluronan/Hyaluronate
A substance found naturally in joint fluid that acts as a shock absorber and lubricant in the knee joint and is necessary for the joint to function properly.
Back to top- Hyaluronic Acid
A substance injected into a knee with osteoarthritis. Serves to restore lubrication and shock absorbing capabilities that have been depleted due to the disease of osteoarthritis.
Back to top- Immunogenic
Relating to or producing an immune response
Back to top- Intraarticular Injections
An injection administered by entering a joint
Back to top- Joint Aspiration
The act of removing a fluid from a joint in the body by a hollow needle connected with a suction syringe
Back to top- Joint Fluid
A transparent, lubricating fluid secreted by a membrane of an articulation (place of union between two or more joints) or bursa (a saclike body cavity between a tendon and bone)
Back to top- Knee Scope
Examination of a knee through an endoscope (an instrument for visualizing the interior of a hollow organ)
Back to top- Magnetic Resonance Imaging (MRI)
A special imaging technique used to image internal structures of the body particularly the soft tissues
Back to top- Molecular Weight
The sum of the atomic weights of all the atoms in a molecule
Back to top- Nonpharmacologic Therapy
A non-drug therapy, such as exercise, with therapeutic value
Back to top- NSAIDs
A nonsteroidal anti-inflammatory drug such as ibuprofen
Back to top- ORTHOVISC®
Ultra-pure natural hyaluronan that is injected intraarticular into the knee and is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics
Back to top- Osteoarthritis
Arthritis typically with onset during middle or old age that is characterized by degenerative (gradual deterioration of joint) and sometimes abnormal growth in the bone and cartilage of one or more joints and a progressive wearing down of opposing joint surfaces with consequent distortion of joint position and is marked symptomatically especially by pain, swelling, and stiffness; abbreviation (OA)
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A bony outgrowth
Back to top- Physiologic Saline
An approximately 0.9 percent solution of sodium chloride; also called normal saline solution
Back to top- Physiotherapy
A therapy that uses physical agents such as exercise, massage and other modalities
Back to top- Placebo
An inert substance used especially in controlled experiments testing the efficacy of another substance such as a drug
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Something that preserves or has the power of preserving
Back to top- Pseudo septic reaction
Severe inflammation of the joint often with significant pain normally occurring 24 to 72 hours after intraarticular injection; often requires clinical intervention
Back to top- Rheologic
Of or relating to the phenomena of flowing matter
Back to top- Spurs
A sharp, bony outgrowth located at the end of a bone
Back to top- Subchondoral
Situated beneath cartilage
Back to top- Synovial Fluid
A lubricating fluid resembling the white of an egg, secreted by certain membranes, as those of the joints; also called joint fluid
Back to top- Synovium
The inner membrane of a joint capsule surrounding a freely movable joint.
Back to top- Total Joint Replacement
Repair of a damaged joint by replacing with a synthetic joint implant, made of either plastic, ceramic, titanium or stainless steel, in an effort to return normal function to affected joint
Back to top- Viscoelasticity
Having the quality of being thick and slow-flowing
Back to top- Viscosity
The property of resistance to flow in a fluid
Back to top- Viscosupplementation Injections
A procedure that replaces diseased synovial fluid in people with osteoarthritis of the knee in an effort to decrease pain, enhance range of motion and increase joint mobility
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